As mentioned earlier in this guide, the benefits of urolithin A are mainly attributed to its potential to kickstart mitochondrial autophagy or mitophagy the process of your body clearing out old, dysfunctional mitochondria and replacing them with new, healthy ones.7 8 14 When dysfunctional mitochondria build up, the production of oxidative stress in the body may increase.8 This, in turn, increases the risk of developing various chronic and degenerative diseases, such as cancer, heart disease, kidney disease, Alzheimers disease, Parkinsons disease, rheumatoid arthritis, and more.15 Besides increasing your disease risk, excess oxidative stress can also lead to: More visible signs of skin aging (fine lines, wrinkles, etc.)15 Increased muscle atrophy26 Reduced muscle force generation26 Neuroinflammation27 Since urolithin A has the potential to help your body clean out dysfunctional mitochondria by supporting mitophagy, it may also be able to lower your risk of health concerns attributed to oxidative stress increasing your healthspan and, possibly, your lifespan
Try over-the-counter nausea remedies If you are trying the above lifestyle changes and need a little extra help to fight the nausea, you may want to consider an over-the-counter nausea remedy
In a 51-year-old man with diabetes mellitus currently taking insulin glargine 15 units twice daily, metformin 1000 mg twice daily, and semaglutide 0.5 mg weekly, whose hemoglobin A1c has fallen from 14 % to 8.2 % over three months, should any of his medications be adjusted?
Vazquez F, Lim JH, Chim H, Bhalla K, Girnun G, Pierce K et al
